Uganda’s Ebola-free: A Triumph of Preparedness and Early Response

Uganda has been declared Ebola-free by the World Health Organization (WHO) after the latest outbreak of the virus claimed almost 60 lives in about five months. The outbreak of the deadly virus was declared over after 42 days without a new case being reported, which is double the incubation period for the virus according to WHO protocols. The highly contagious disease spreads through direct contact with bodily fluids, and causes fatigue, fever and bleeding from the eyes and nose. It kills almost half of those who become infected.

This outbreak, which involved the Ebola Sudan strain of the virus, began in September and killed 56 people, including seven healthcare workers, and caused 142 confirmed infections. The virus spread through parts of the country, with officials hesitant to impose another ban on movement within the country in the wake of recent coronavirus lockdowns. Only in December were a curfew and restrictions on movement introduced in the affected districts. By then, the United States and other countries had issued orders to screen all travelers from Uganda arriving at their airports.

The acting director of Africa’s Centers for Disease Control, Ahmed Ogwell Ouma, has praised the Ugandan government for its “excellent” coordination of Ebola containment measures, saying it had taken approximately 70 days to bring the outbreak under control. African health authorities had prioritized preparedness for the deadly virus after devastating outbreaks of the Ebola Zaire strain in Guinea, Liberia and Sierra Leone between 2013 and 2016 killed more than 11,300 people. Those outbreaks inspired global fear that air travel could allow the virus to spread across the world in a matter of hours. That fear helped galvanize research and funding for vaccines to protect against the Zaire strain of the virus.

Three candidate vaccines in development for the Ebola Zaire strain were sent to Uganda, with the first arriving on December 8, to be evaluated in a clinical trial being run by the Makerere University Lung Institute, as there is currently no vaccine proven to be effective against the Sudan strain of the virus. Critics have said an opportunity was missed as the candidate vaccines only arrived as the virus was waning. The delays meant a chance to trial the drugs amid an evolving outbreak was missed. However, the limited trial did prove the vaccines safe to use on humans. In December, doctors discharged the last known Ebola patient in Uganda from hospital, allowing President Yoweri Museveni to lift all Ebola-related restrictions and curfews for the holiday season.

“Today we join the Government of Uganda to declare the end of the Sudan Ebola Virus Outbreak in the Country,” said Dr Matshidiso Moeti, WHO’s Regional Director for Africa. The WHO’s Moeti further added, “With no vaccines and therapeutics, this was one of the most challenging Ebola outbreaks in the past five years, but Uganda stayed the course and continuously fine-tuned its response. Two months ago, it looked as if Ebola would cast a dark shadow over the country well into 2023, as the outbreak reached major cities such as Kampala and Jinja, but this win starts off the year on a note of great hope for Africa.”

The end of the Ebola outbreak in Uganda is certainly a cause for celebration and relief, but it also serves as a reminder of the importance of preparedness and early response in the face of deadly epidemics. The Ebola virus is a highly contagious and deadly disease, and it is essential that countries and international organizations take the necessary steps to prevent and contain outbreaks as quickly as possible. The WHO’s announcement of Uganda being Ebola-free is an encouraging sign for the continent of Africa and the rest of the world, showing that with proper coordination and response, it is possible to overcome even the most challenging of outbreaks.

 

Effects of High Blood Pressure (Hypertension)

 

 

What is blood pressure?

When the heart pumps blood through the arteries, the blood puts pressure on the artery walls. This is known as blood pressure.

Blood pressure is the pressure of blood pushing against the walls of your arteries. Arteries carry blood from your heart to other parts of your body.

Your blood pressure normally rises and falls throughout the day.

What do blood pressure numbers mean?

Blood pressure is measured using two numbers:

The first number, called systolic blood pressure, measures the pressure in your arteries when your heart beats.

The second number, called diastolic blood pressure, measures the pressure in your arteries when your heart rests between beats.

If the measurement reads 120 systolic and 80 diastolic, you would say, “120 over 80,” or write, “120/80 mmHg.”

What are normal blood pressure numbers?

A normal blood pressure level is less than 120/80 mmHg.1

No matter your age, you can take steps each day to keep your blood pressure in a healthy range.

What is high blood pressure (hypertension)?

High blood pressure, also called hypertension, is blood pressure that is higher than normal. Your blood pressure changes throughout the day based on your activities. Having blood pressure measures consistently above normal may result in a diagnosis of high blood pressure (or hypertension).

The higher your blood pressure levels, the more risk you have for other health problems, such as heart diseaseheart attack, and stroke.

Your health care team can diagnose high blood pressure and make treatment decisions by reviewing your systolic and diastolic blood pressure levels and comparing them to levels found in certain guidelines.

The guidelines used to diagnose high blood pressure may differ from health care professional to health care professional:

  • Some health care professionals diagnose patients with high blood pressure if their blood pressure is consistently 140/90 mm Hg or higher.2 This limit is based on a guideline released in 2003, as seen in the table below.
  • Other health care professionals diagnose patients with high blood pressure if their blood pressure is consistently 130/80 mm Hg or higher.1 This limit is based on a guideline released in 2017, as seen in the table below.
Blood Pressure Levels
Blood Pressure Levels
The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (2003 Guideline)2 The American College of Cardiology/American Heart Association Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults (2017 Guideline)1
Normal systolic: less than 120 mm Hg
diastolic: less than 80 mm Hg
Normal systolic: less than 120 mm Hg
diastolic: less than 80 mm Hg
At Risk (prehypertension) systolic: 120–139 mm Hg
diastolic: 80–89 mm Hg
Elevated systolic: 120–129 mm Hg
diastolic: less than 80 mm Hg
High Blood Pressure (hypertension) systolic: 140 mm Hg or higher
diastolic: 90 mm Hg or higher
High blood pressure (hypertension) systolic: 130 mm Hg or higher
diastolic: 80 mm Hg or higher

If you are diagnosed with high blood pressure, talk with your health care team about your blood pressure levels and how these levels affect your treatment plan.

What are the signs and symptoms of high blood pressure?

High blood pressure usually has no warning signs or symptoms, and many people do not know they have it. Measuring your blood pressure is the only way to know whether you have high blood pressure.

What causes high blood pressure?

High blood pressure usually develops over time. It can happen because of unhealthy lifestyle choices, such as not getting enough regular physical activity. Certain health conditions, such as diabetes and having obesity, can also increase the risk for developing high blood pressure. High blood pressure can also happen during pregnancy.

Hypertension complications: stroke, heart attack, kidney damage.

You can manage your blood pressure to lower your risk for serious health problems that may affect your heart, brain, kidneys, and eyes.

What problems does high blood pressure cause?

High blood pressure can damage your health in many ways. It can seriously hurt important organs like your heart, brain, kidneys, and eyes.

The good news is that, in most cases, you can manage your blood pressure to lower your risk for serious health problems.

Heart Attack and Heart Disease

High blood pressure can damage your arteries by making them less elastic, which decreases the flow of blood and oxygen to your heart and leads to heart disease. In addition, decreased blood flow to the heart can cause:

  • Chest pain, also called angina.
  • Heart attack, which happens when the blood supply to your heart is blocked and heart muscle begins to die without enough oxygen. The longer the blood flow is blocked, the greater the damage to the heart.
  • Heart failure, a condition that means your heart can’t pump enough blood and oxygen to your other organs.

Stroke and Brain Problems

High blood pressure can cause the arteries that supply blood and oxygen to the brain to burst or be blocked, causing a stroke. Brain cells die during a stroke because they do not get enough oxygen. Stroke can cause serious disabilities in speech, movement, and other basic activities. A stroke can also kill you.

Having high blood pressure, especially in midlife, is linked to having poorer cognitive function and dementia later in life. Learn more about the link between high blood pressure and dementia from the National Institutes of Health’s Mind Your Risks®external icon campaign.

Kidney Disease

Adults with diabetes, high blood pressure, or both have a higher risk of developing chronic kidney disease than those without these conditions.

How do I know if I have high blood pressure?

There’s only one way to know if you have high blood pressure: Have a doctor or other health professional measure it. Measuring your blood pressure is quick and painless.

Talk with your health care team about regularly measuring your blood pressure at home, also called self-measured blood pressure (SMBP) monitoring.

High blood pressure is called the “silent killer” because it usually has no warning signs or symptoms, and many people do not know they have it.

What can I do to prevent or manage high blood pressure?

Many people with high blood pressure can lower their blood pressure into a healthy range or keep their numbers in a healthy range by making lifestyle changes. Talk with your health care team about

  • Getting at least 150 minutes of physical activity each week (about 30 minutes a day, 5 days a week)
  • Not smoking
  • Eating a healthy diet, including limiting sodium (salt) and alcohol
  • Keeping a healthy weight
  • Managing stress

Learn more about ways to manage and prevent high blood pressure.

In addition to making positive lifestyle changes, some people with high blood pressure need to take medicine to manage their blood pressure. Learn more about medicines for high blood pressure.

Talk with your health care team right away if you think you have high blood pressure or if you’ve been told you have high blood pressure but do not have it under control.

By taking action to lower your blood pressure, you can help protect yourself against heart disease and stroke, also sometimes called cardiovascular disease (CVD).

Learn More

Measure Your Blood Pressure

Learn how and why to get your blood pressure checked.

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Know Your Risk for High Blood Pressure

Find out what increases your risk for high blood pressure.

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Prevent and Manage Your Blood Pressure

Learn what you can do to keep a healthy blood pressure.

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